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Membrane Transport and Antitumor Activity of Pirarubicin, and Comparison with Those of Doxorubicin
We have compared the membrane transport and antitumor activity of pirarubicin with those of doxorubicin in M5076 ovarian sarcoma, which exhibits low sensitivity to doxorubicin. Pirarubicin was rapidly taken up by M5076 cells and the intracellular concentration of pirarubicin reached more than 2.5‐fo...
Autores principales: | Sugiyama, Tomomi, Sadzuka, Yasuyuki, Nagasawa, Kazuki, Ohnishi, Noriaki, Yokoyama, Teruyoshi, Sonobe, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926135/ https://www.ncbi.nlm.nih.gov/pubmed/10470291 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00814.x |
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