Prevention by Chitosan of Myelotoxicity, Gastrointestinal Toxicity and Immunocompetent Organic Toxicity Induced by 5‐Fluorouracil without Loss of Antitumor Activity in Mice

We examined the antitumor activity and side effects (myelotoxicity, immunocompetent organic toxicity and gastrointestinal toxicity) of combined treatment with the cancer chemotherapy drug 5‐fluorouracil (5‐FU) and dietary fiber chitosan in sarcoma 180‐bearing mice. 5‐FU (12.5 mg/kg×2/ day) plus chit...

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Detalles Bibliográficos
Autores principales: Kimura, Yoshiyuki, Okuda, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926136/
https://www.ncbi.nlm.nih.gov/pubmed/10470290
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00813.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926136/
https://www.ncbi.nlm.nih.gov/pubmed/10470290
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00813.x

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