Detection of Hypoxic Cells in Murine Tumors Using the Comet Assay: Comparison with a Conventional Radiobiological Assay

The comet (single‐cell electrophoresis) assay has been developed as a method for measuring DNA damage in single cells after irradiation. We have developed our own methods and image analysis system for the comet assay to identify hypoxic fractions. In vitro, we tested our system using a cultured tumo...

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Detalles Bibliográficos
Autores principales: Shibuya, Keiko, Sasai, Keisuke, Xie, Xuejun, Utsumi, Hiroshi, Shibata, Toru, Hiraoka, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926142/
https://www.ncbi.nlm.nih.gov/pubmed/10543261
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00830.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926142/
https://www.ncbi.nlm.nih.gov/pubmed/10543261
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00830.x

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