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Loss of Heterozygosity in (Lewis×F344)F(1) Rat Urinary Bladder Tumors Induced with N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Followed by Dimethylarsinic Acid or Sodium L‐Ascorbate
Dimethylarsinic acid (DMA), a main metabolite of arsenicals which are carcinogenic in man, exerts tumor‐promoting activity on rat urinary bladder carcinogenesis initiated with N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN). Sodium L‐ascorbate (Na‐AsA) is also a strong tumor promoter in this animal mode...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926144/ https://www.ncbi.nlm.nih.gov/pubmed/10543252 http://dx.doi.org/10.1111/j.1349-7006.1999.tb00821.x |