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Loss of Heterozygosity in (Lewis×F344)F(1) Rat Urinary Bladder Tumors Induced with N‐Butyl‐N‐(4‐hydroxybutyl)nitrosamine Followed by Dimethylarsinic Acid or Sodium L‐Ascorbate

Dimethylarsinic acid (DMA), a main metabolite of arsenicals which are carcinogenic in man, exerts tumor‐promoting activity on rat urinary bladder carcinogenesis initiated with N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine (BBN). Sodium L‐ascorbate (Na‐AsA) is also a strong tumor promoter in this animal mode...

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Detalles Bibliográficos
Autores principales: Chen, Tianxin, Na, Yifei, Wanibuchi, Hideki, Yamamoto, Shinji, Lee, Chyi Chia R., Fukushima, Shoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926144/
https://www.ncbi.nlm.nih.gov/pubmed/10543252
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00821.x