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A Novel Combretastatin A‐4 Derivative, AC‐7700, Shows Marked Antitumor Activity against Advanced Solid Tumors and Orthotopically Transplanted Tumors

AC‐7700, a novel combretastatin A‐4 derivative, suppresses the growth of solid tumors by inhibiting tumor perfusion. We evaluated the antitumor activity of AC‐7700 on solid tumors in two experimental models, an advanced tumor model (murine colon 26 (c26) adenocarcinoma, colon 38 (c38) adenocarcinoma...

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Detalles Bibliográficos
Autores principales: Nihei, Yukio, Suga, Yasuyo, Morinaga, Yoshihiro, Ohishi, Kazuo, Okano, Akira, Ohsumi, Koji, Hatanaka, Toshihiro, Nakagawa, Ryusuke, Tsuji, Takashi, Akiyama, Yukio, Saito, Sachiko, Hori, Katsuyoshi, Sato, Yasufumi, Tsuruo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926154/
https://www.ncbi.nlm.nih.gov/pubmed/10551333
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00850.x