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Rare‐type Mutations of MMAC1 Tumor Suppressor Gene in Human Glioma Cell Lines and Their Tumors of Origin

A total of 10 glioma cell lines were examined to evaluate the status of the MMAC1 gene, a candidate tumor suppressor gene. Six cell lines showed mutations with presumed loss of heterozygosity and 1 cell line showed no mRNA expression. The 6 mutations consisted of 3 3‐bp deletions (codons 17, 101 or...

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Detalles Bibliográficos
Autores principales: Zhang, Shu‐Jing, Endo, Sumio, Ichikawa, Tomio, Yoshimura, Junichi, Onda, Kiyoshi, Tanaka, Ryuichi, Washiyama, Kazuo, Kumanishi, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926156/
https://www.ncbi.nlm.nih.gov/pubmed/10551321
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00838.x