Hypomethylation of CpG Sites and c‐myc Gene Overexpression in Hepatocellular Carcinomas, but Not Hyperplastic Nodules, Induced by a Choline‐deficient L‐Amino Acid‐defined Diet in Rats

We have investigated aberrant methylation of CpG nucleotides (CpG sites) and gene expression of c‐myc during hepatocarcinogenesis induced by a choline‐deficient, L‐amino acid‐defined (CDAA) diet in rats. Male Fischer 344 rats, 6 weeks old, were continuously given a CDAA diet for 50 and 75 weeks and...

Descripción completa

Detalles Bibliográficos
Autores principales: Tsujiuchi, Toshifumi, Tsutsumi, Masahiro, Sasaki, Yasutaka, Takahama, Makoto, Konishi, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926157/
https://www.ncbi.nlm.nih.gov/pubmed/10551317
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00834.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926157/
https://www.ncbi.nlm.nih.gov/pubmed/10551317
http://dx.doi.org/10.1111/j.1349-7006.1999.tb00834.x

Ejemplares similares