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Dihydropyrimidine Dehydrogenase and Messenger RNA Levels in Gastric Cancer: Possible Predictor for Sensitivity to 5‐Fluorouracil

We investigated the correlation between tumor sensitivity to 5‐fluorouracil (5‐FU) and enzymatic activities of thymidylate synthetase (TS) and dihydropyrimidine dehydrogenase (DPD) in human gastric cancer specimens. Forty‐one patients with advanced gastric cancer gave informed consent and were enrol...

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Detalles Bibliográficos
Autores principales: Ishikawa, Yoichiro, Kubota, Tetsuro, Otani, Yoshihide, Watanabe, Masahiko, Teramoto, Tatsuo, Kumai, Koichiro, Takechi, Teiji, Okabe, Hiroyuki, Fukushima, Masakazu, Kitajima, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926227/
https://www.ncbi.nlm.nih.gov/pubmed/10744051
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00866.x