Adenovirus‐mediated Gene Transduction of IkB or IkB Plus Bax Gene Drastically Enhances Tumor Necrosis Factor (TNF)‐induced Apoptosis in Human Gliomas

Tumor necrosis factor‐α (TNF), which was initially supposed to be a promising cancer therapeutic reagent, does not kill most types of cancer cells partly due to the activation of an anti‐apoptotic gene, NF‐kB. NF‐kB forms an inactive complex with the inhibitor kappa B alpha (IkBα), which is rapidly...

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Detalles Bibliográficos
Autores principales: Shinoura, Nobusada, Yamamoto, Naoki, Yoshida, Yoko, Fujita, Takashi, Saito, Nobuto, Asai, Akio, Kirino, Takaaki, Hamada, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926230/
https://www.ncbi.nlm.nih.gov/pubmed/10744043
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00858.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926230/
https://www.ncbi.nlm.nih.gov/pubmed/10744043
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00858.x

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