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In vitro Antitumor Activity, Intracellular Accumulation, and DNA Adduct Formation of cis‐[((1R, 2R)‐1,2‐Cyclohexanediamine‐N, N')bis(myristato)] Platinum (II) Suspended in Lipiodol

SM‐11355, cis‐[((1R,2R)‐1,2‐cyclohexanediamine‐N,N')bis(myristato)] platinum (II), is a lipophilic platinum complex under clinical development that targets primary hepatocellular carcinoma using Lipiodol as a carrier. SM‐11355 was compared with cisplatin (CDDP) using an in vitro evaluation syst...

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Detalles Bibliográficos
Autores principales: Kishimoto, Shuichi, Miyazawa, Kenji, Fukushima, Shoji, Takeuchi, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926231/
https://www.ncbi.nlm.nih.gov/pubmed/10744050
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00865.x