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Adenovirus‐mediated Transfer of Fas Ligand Gene Augments Radiation‐induced Apoptosis in U‐373MG Glioma Cells

Most malignant astrocytomas (gliomas) express a high level of Fas, whereas the surrounding normal tissues such as neurons and astrocytes express a very low level of Fas. Thus, transduction of Fas ligand would selectively kill malignant astrocytoma cells. On the other hand, glioma cells harboring p53...

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Detalles Bibliográficos
Autores principales: Shinoura, Nobusada, Yamamoto, Naoki, Asai, Akio, Kirino, Takaaki, Hamada, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926259/
https://www.ncbi.nlm.nih.gov/pubmed/11050476
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00883.x