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Increased Frequencies of Gene and Chromosome Mutations after X‐Irradiation in Mouse Embryonal Carcinoma Cells Transfected with the bcl‐2 Gene

Preimplantation stage mouse embryos are known to be highly sensitive to the killing effect of DNA damaging agents such as radiation. Interestingly, however, this stage of development is well protected from radiation induction of malformation and carcinogenesis in postnatal life. In recent years, it...

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Detalles Bibliográficos
Autores principales: Taga, Masataka, Shiraishi, Kazunori, Shimura, Tsutomu, Uematsu, Norio, Oshimura, Mitsuo, Niwa, Ohtsura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926261/
https://www.ncbi.nlm.nih.gov/pubmed/11050469
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00876.x