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Propofol Inhibits HeLa Cells by Impairing Autophagic Flux via AMP-Activated Protein Kinase (AMPK) Activation and Endoplasmic Reticulum Stress Regulated by Calcium

BACKGROUND: Propofol has antitumor effects against various cancers. However, the mechanism of action of propofol in HeLa human cervical cancer cells has not been elucidated. MATERIAL/METHODS: We treated HeLa human cervical cancer cells with different concentrations of propofol. Cell viability was ev...

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Detalles Bibliográficos
Autores principales: Chen, Xi, Li, Kai, Zhao, Guoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926273/
https://www.ncbi.nlm.nih.gov/pubmed/29667627
http://dx.doi.org/10.12659/MSM.909144