Trans‐regulated Silencing and Reactivation of TP53 Tumor Suppressor Gene in Malignant Transformation and Its Reversion

Despite growing interest in the methylation‐mediated silencing of tumor suppressor genes in the neoplastic process, its signaling mechanism remains largely unknown. Here we show in a cultured murine cell line system that the silencing and reactivation of tumor suppressor gene TP53 were reversibly co...

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Detalles Bibliográficos
Autores principales: Yang, Lichun, Sasaki, Masao S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926277/
https://www.ncbi.nlm.nih.gov/pubmed/11092975
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00893.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926277/
https://www.ncbi.nlm.nih.gov/pubmed/11092975
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00893.x

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