Protection against Malignant Progression of Spontaneously Developing Liver Tumors in Transgenic Mice Expressing O(6)‐Methylguanine‐DNA Methyltransferase

To study the effect of O(6)‐methylguanine‐DNA methyltransferase (MGMT) on carcinogenesis, we have previously generated MGMT transgenic mice overexpressing the bacterial MGMT gene, ada, and demonstrated that high MGMT levels in the liver suppress induction of liver tumors after treatment with an alky...

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Detalles Bibliográficos
Autores principales: Qin, Xiusheng, Zhang, Shaomin, Matsukuma, Shoichi, Zarkovic, Mirjana, Shimizu, Seiichiro, Ishikawa, Takatoshi, Nakatsuru, Yoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://www.ncbi.nlm.nih.gov/pubmed/11092970
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926285/
https://www.ncbi.nlm.nih.gov/pubmed/11092970
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00888.x

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