Critical Role of Extracellular Signal‐regulated Kinase (ERK) Phosphorylation in Novel Vitamin K Analog‐induced Cell Death

In the present study, we show that 2‐(2‐hydroxyethylsulfaryl)‐3‐methyl‐1,4‐naphthoquinone, or CPD 5, is a potent growth inhibitor for pancreas cancer cell lines (ID(50): 21.4±3.8, 31.8±2.7 and 55.2±4.5 μM for MiaPaCa, Panc‐1 and BxPc3, respectively). It induced protein tyrosine phosphorylation of he...

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Detalles Bibliográficos
Autores principales: Osada, Shinji, Carr, Brian I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926301/
https://www.ncbi.nlm.nih.gov/pubmed/11123423
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00911.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926301/
https://www.ncbi.nlm.nih.gov/pubmed/11123423
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00911.x

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