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Critical Role of Extracellular Signal‐regulated Kinase (ERK) Phosphorylation in Novel Vitamin K Analog‐induced Cell Death
In the present study, we show that 2‐(2‐hydroxyethylsulfaryl)‐3‐methyl‐1,4‐naphthoquinone, or CPD 5, is a potent growth inhibitor for pancreas cancer cell lines (ID(50): 21.4±3.8, 31.8±2.7 and 55.2±4.5 μM for MiaPaCa, Panc‐1 and BxPc3, respectively). It induced protein tyrosine phosphorylation of he...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2000
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926301/ https://www.ncbi.nlm.nih.gov/pubmed/11123423 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00911.x |