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Bax Induction Activates Apoptotic Cascade via Mitochondrial Cytochrome c Release and Bax Overexpression Enhances Apoptosis Induced by Chemotherapeutic Agents in DLD‐1 Colon Cancer Cells

Cancer cells express different levels of apoptosis‐promoting Bax protein. The present study evaluated whether induction of Bax initiates apoptosis and whether Bax overexpression enhances apoptosis induced by several chemotherapeutic agents in DLD‐1 colon cancer cells, which originally express a high...

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Detalles Bibliográficos
Autores principales: Kobayashi, Tohru, Sawa, Hidehiko, Morikawa, Jun, Zhang, Wei, Shiku, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926309/
https://www.ncbi.nlm.nih.gov/pubmed/11123425
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00913.x