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Increased Expression of Cyclin D1, Cyclin E and p21(Cip1) Associated with Decreased Expression of p27(Kip1) in Chemically Induced Rat Mammary Carcinogenesis

We induced rat mammary tumors in 7‐week‐old female Sprague‐Dawley rats by intragastric administration of 7,12‐dimethylbenz(a)anthracene (DMBA), and analyzed by immunohistochemistry the expression of cyclin D1, cyclin E, p21(Cip1), and p27(Kip1) in carcinomas, atypical tumors, and benign tumors as we...

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Detalles Bibliográficos
Autores principales: Jang, Tae Jung, Kang, Myung Soo, Kim, Heesoo, Kim, Dong Hoon, Lee, Jong Im, Kim, Jung Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926312/
https://www.ncbi.nlm.nih.gov/pubmed/11123420
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00908.x