p53‐independent Induction of p21 (WAF1/CIP1), Reduction of Cyclin B1 and G2/M Arrest by the Isoflavone Genistein in Human Prostate Carcinoma Cells

Genistein, a natural isoflavonoid phytoestrogen, is a strong inhibitor of protein tyrosine kinase and DNA topoisomerase II activities. Genistein has been shown to have anticancer proliferation, differentiation and chemopreventive effects. In the present study, we have addressed the mechanism of acti...

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Detalles Bibliográficos
Autores principales: Choi, Yung Hyun, Lee, Won Ho, Park, Kun‐Young, Zhang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926325/
https://www.ncbi.nlm.nih.gov/pubmed/10761703
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00928.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926325/
https://www.ncbi.nlm.nih.gov/pubmed/10761703
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00928.x

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