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p53‐independent Induction of p21 (WAF1/CIP1), Reduction of Cyclin B1 and G2/M Arrest by the Isoflavone Genistein in Human Prostate Carcinoma Cells
Genistein, a natural isoflavonoid phytoestrogen, is a strong inhibitor of protein tyrosine kinase and DNA topoisomerase II activities. Genistein has been shown to have anticancer proliferation, differentiation and chemopreventive effects. In the present study, we have addressed the mechanism of acti...
Autores principales: | Choi, Yung Hyun, Lee, Won Ho, Park, Kun‐Young, Zhang, Lijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926325/ https://www.ncbi.nlm.nih.gov/pubmed/10761703 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00928.x |
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