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BRCA1 Expression Status in Relation to DNA Methylation of the BRCA1 Promoter Region in Sporadic Breast Cancers

To understand the biological role of BRCA1 in sporadic breast cancers, the relationship between DNA methylation of the BRCA1 Promoter region and BRCA1 expression was studied using molecular biological and immunohistochemical methods. Furthermore, BRCA1 expression was compared with the expression of...

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Detalles Bibliográficos
Autores principales: Niwa, Youko, Oyama, Tetsunari, Nakajima, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926373/
https://www.ncbi.nlm.nih.gov/pubmed/10835497
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00976.x