MDM2 Overexpression with Alteration of the p53 Protein and Gene Status in Oral Carcinogenesis

In this study, to better understand the mechanism of oral squamous cell carcinoma (SCC) carcinogenesis, alterations of the p53 gene and overexpression of MDM2 and p53 were analyzed in 38 oral SCC samples. Twelve of the 38 specimens revealed mutant‐type p53. Moreover, coexpression of MDM2 and p53 was...

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Detalles Bibliográficos
Autores principales: Li, Xiao‐Jun, Murai, Mutsuhiko, Koyama, Takashi, Li, Xiao‐Jin, Wang, Dong‐Yu, Hashimoto, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926374/
https://www.ncbi.nlm.nih.gov/pubmed/10835493
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00972.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926374/
https://www.ncbi.nlm.nih.gov/pubmed/10835493
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00972.x

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