Cargando…

Infrequent Mutation of the hBUB1 and hBUBR1 Genes in Human Lung Cancer

Mitotic checkpoint defects of the cell cycle have been implicated in the development of human cancers. Since hBUB1 and hBUBR1, whose products function in the spindle checkpoint pathway, have been shown to be mutated in a subset of colon cancers with chromosomal instability, we investigated the contr...

Descripción completa

Detalles Bibliográficos
Autores principales: Sato, Mitsuo, Sekido, Yoshitaka, Horio, Yoshitsugu, Takahashi, Masahide, Saito, Hidehiko, Minna, John D., Shimokata, Kaoru, Hasegawa, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926378/
https://www.ncbi.nlm.nih.gov/pubmed/10835495
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00974.x