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Infrequent Mutation of the hBUB1 and hBUBR1 Genes in Human Lung Cancer
Mitotic checkpoint defects of the cell cycle have been implicated in the development of human cancers. Since hBUB1 and hBUBR1, whose products function in the spindle checkpoint pathway, have been shown to be mutated in a subset of colon cancers with chromosomal instability, we investigated the contr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926378/ https://www.ncbi.nlm.nih.gov/pubmed/10835495 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00974.x |