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Usefulness of Tirapazamine as a Combined Agent in Chemoradiation and Thermo‐chemoradiation Therapy at Mild Temperatures: Reference to the Effect on Intratumor Quiescent Cells

C3H/He mice bearing SCC VII tumors received 5‐bromo‐2′‐deoxyuridine (BrdU) continuously for 5 days via implanted mini‐osmotic pumps to label all proliferating (P) cells. The mice then received one of six different DNA‐damaging agents with or without mild temperature hyperthermia (40°C, 30 min, MTH)....

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Detalles Bibliográficos
Autores principales: Masunaga, Shin‐ichiro, Ono, Koji, Suzuki, Minoru, Kinashi, Yuko, Takagaki, Masao, Hori, Hitoshi, Kasai, Soko, Nagasawa, Hideko, Uto, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926384/
https://www.ncbi.nlm.nih.gov/pubmed/10835503
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00982.x