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Ras and Signal Transducer and Activator of Transcription (STAT) Are Essential and Sufficient Downstream Components of Janus Kinases in Cell Proliferation

Cytokines exert their activities in cell growth and differentiation by binding specific cell membrane receptors. Janus kinases (JAKs) are cytoplasmic protein tyrosine kinases that physically interact with intracellular domains of the cytokine receptors and they play crucial roles in transducing sign...

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Detalles Bibliográficos
Autores principales: Mizuguchi, Rumiko, Noto, Satoshi, Yamada, Masafumi, Ashizawa, Satoshi, Higashi, Hideaki, Hatakeyama, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926385/
https://www.ncbi.nlm.nih.gov/pubmed/10835498
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00977.x