Identification and Characterization of a Deletion Mutant of DNA Topoisomerase I mRNA in a Camptothecin‐resistant Subline of Human Colon Carcinoma

In previous studies, we established two camptothecin (CPT)‐resistant sublines, HT‐29/CPT and St‐4/CPT, from the human colon cancer cell line HT‐29 and the human stomach cancer cell line St‐4, respectively. Cellular contents of DNA topoisomerase I (topo I) in the resistant cells were eight‐fold less...

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Detalles Bibliográficos
Autores principales: Yanase, Kae, Sugimoto, Yoshikazu, Tsukahara, Satomi, Oh‐hara, Tomoko, Andoh, Toshiwo, Tsuruo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926386/
https://www.ncbi.nlm.nih.gov/pubmed/10835501
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00980.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926386/
https://www.ncbi.nlm.nih.gov/pubmed/10835501
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00980.x

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