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Multidrug Resistance Reversal Activity of Taxoids from Taxus cuspidate in KB‐C2 and 2780AD Cells

Some non‐taxol‐type taxoids having neither an oxetane ring at C‐4 and C‐5 nor an N‐acylphenylisoserine group at C‐13, such as taxuspine C, 2′‐desacetoxyaustrospicatine, and 2‐desacetoxytaxinine J, which were isolated from the Japanese yew Taxus cuspidata, increased cellular accumulation of vincristi...

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Detalles Bibliográficos
Autores principales: Kobayashi, Jun'ichi, Shigemori, Hideyuki, Hosoyama, Hirokazu, Chen, Zhe‐Sheng, Akiyama, Shin‐ichi, Naito, Mikihiko, Tsuruo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926394/
https://www.ncbi.nlm.nih.gov/pubmed/10874217
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00993.x