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Suppression by Flavonoids of Cyclooxygenase‐2 Promoter‐dependent Transcriptional Activity in Colon Cancer Cells: Structure‐Activity Relationship

Cyclooxygenase‐2 (COX‐2) plays an important role in carcinogenesis. Investigation of the suppressive action of twelve flavonoids of different chemical classes on the transcriptional activity of the COX‐2 gene in human colon cancer DLD‐1 cells using a reporter gene assay have revealed quercetin to be...

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Detalles Bibliográficos
Autores principales: Mutoh, Michihiro, Takahashi, Mami, Fukuda, Kazunori, Komatsu, Hajime, Enya, Takeji, Matsushima‐Hibiya, Yuko, Mutoh, Hiroshi, Sugimura, Takashi, Wakabayashi, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926411/
https://www.ncbi.nlm.nih.gov/pubmed/10920275
http://dx.doi.org/10.1111/j.1349-7006.2000.tb01000.x