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Suppression by Flavonoids of Cyclooxygenase‐2 Promoter‐dependent Transcriptional Activity in Colon Cancer Cells: Structure‐Activity Relationship
Cyclooxygenase‐2 (COX‐2) plays an important role in carcinogenesis. Investigation of the suppressive action of twelve flavonoids of different chemical classes on the transcriptional activity of the COX‐2 gene in human colon cancer DLD‐1 cells using a reporter gene assay have revealed quercetin to be...
Autores principales: | Mutoh, Michihiro, Takahashi, Mami, Fukuda, Kazunori, Komatsu, Hajime, Enya, Takeji, Matsushima‐Hibiya, Yuko, Mutoh, Hiroshi, Sugimura, Takashi, Wakabayashi, Keiji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926411/ https://www.ncbi.nlm.nih.gov/pubmed/10920275 http://dx.doi.org/10.1111/j.1349-7006.2000.tb01000.x |
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