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Characterization of the Interaction of TZT‐1027, a Potent Antitumor Agent, with Tubulin
TZT‐1027, a derivative of dolastatin 10 isolated from the Indian Ocean sea hare Dolabella auricularia in 1987 by Pettit et al., is a potent antimicrotubule agent. We have compared the activity of TZT‐1027 with that of dolastatin 10 as well as the vinca alkaloids vinblastine (VLB), vincristine (VCR)...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926414/ https://www.ncbi.nlm.nih.gov/pubmed/10920282 http://dx.doi.org/10.1111/j.1349-7006.2000.tb01007.x |