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p53 Mutations in Prostatic Intraepithelial Neoplasia and Concurrent Carcinoma: Analysis of Laser Capture Microdissected Specimens from Non‐transition and Transition Zones

Prostatic intraepithelial neoplasia (PIN) is characterized by intraluminal proliferation of epithelial cells and is divided into high‐grade (HGPIN) and low‐grade (LGPIN) lesions. HGPIN is regarded as the most likely precursor of prostatic cancer (PCA). Microdissected DNA selectively extracted from p...

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Detalles Bibliográficos
Autores principales: Takayama, Hitoshi, Shin, Masaru, Nonomura, Norio, Okuyama, Akihiko, Aozasa, Katsuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926450/
https://www.ncbi.nlm.nih.gov/pubmed/11011123
http://dx.doi.org/10.1111/j.1349-7006.2000.tb01038.x