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Dose‐ and Sex‐related Carcinogenesis by N‐Bis(2‐hydroxypropyl)nitrosamine in Wistar Rats
An initiation‐promotion medium‐term bioassay for detection of chemical carcinogens, developed in the male F344 rat, uses 0.1% N‐bis(2‐hydroxypropyl)nitrosamine (DHPN) among five genotoxic chemicals for the initiation of carcinogenesis in multiple organs. To establish this bioassay in the Wistar stra...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2000
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926461/ https://www.ncbi.nlm.nih.gov/pubmed/10804283 http://dx.doi.org/10.1111/j.1349-7006.2000.tb00954.x |