Schedule‐dependent Interactions between Raltitrexed and Cisplatin in Human Carcinoma Cell Lines in vitro

Raltitrexed (‘Tomudex”) is a new anticancer agent which inhibits thymidylate synthase. To provide a rational basis for clinical trial design of the combination of raltitrexed and cisplatin, we studied the cytotoxic effects of this combination using various schedules in vitro and four human colon can...

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Detalles Bibliográficos
Autores principales: Kano, Yasuhiko, Akutsu, Miyuki, Suzuki, Kenichi, Yazawa, Yasuo, Tsunoda, Saburo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2000
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://www.ncbi.nlm.nih.gov/pubmed/10804291
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926465/
https://www.ncbi.nlm.nih.gov/pubmed/10804291
http://dx.doi.org/10.1111/j.1349-7006.2000.tb00962.x

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