High Expression of Thymidylate Synthase Leads to Resistance to 5‐Fluorouracil in Biliary Tract Carcinoma in vitro

To evaluate the effect of chemotherapy of 5‐fluorouracil (5‐FU) in human biliary tract carcinoma, we studied 5‐FU sensitivity, thymidylate synthase (TS) content, and dihydropyrimidine dehydroge‐nase (DPD) activity in 4 human biliary tract carcinoma cell lines compared to 12 various digestive carcino...

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Detalles Bibliográficos
Autores principales: Habara, Kazuto, Ajiki, Tetsuo, Kamigaki, Takashi, Nakamura, Takeshi, Kuroda, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926613/
https://www.ncbi.nlm.nih.gov/pubmed/11676864
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01068.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926613/
https://www.ncbi.nlm.nih.gov/pubmed/11676864
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01068.x

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