Reversal of Multidrug Resistance by Novel Nitrophenyl Pyrones, SNF4435C and D

SNF4435C and D, novel immunosuppressants produced by a strain of Streptomyces spectabilis, were examined for their reversing effects in vitro on various multidrug‐resistant (MDR) tumor cells overexpressing P‐glycoprotein. These two compounds in the range of 3–10 [jM completely reversed the resistanc...

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Detalles Bibliográficos
Autores principales: Kurosawa, Kazuhiko, Takahashi, Kosaku, Tsuda, Eisuke, Tomida, Akihiro, Tsuruo, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926656/
https://www.ncbi.nlm.nih.gov/pubmed/11714449
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02145.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926656/
https://www.ncbi.nlm.nih.gov/pubmed/11714449
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02145.x

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