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Reversal of Multidrug Resistance by Novel Nitrophenyl Pyrones, SNF4435C and D
SNF4435C and D, novel immunosuppressants produced by a strain of Streptomyces spectabilis, were examined for their reversing effects in vitro on various multidrug‐resistant (MDR) tumor cells overexpressing P‐glycoprotein. These two compounds in the range of 3–10 [jM completely reversed the resistanc...
Autores principales: | Kurosawa, Kazuhiko, Takahashi, Kosaku, Tsuda, Eisuke, Tomida, Akihiro, Tsuruo, Takashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926656/ https://www.ncbi.nlm.nih.gov/pubmed/11714449 http://dx.doi.org/10.1111/j.1349-7006.2001.tb02145.x |
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