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A Potential Use of a Synthetic Retinoid TAC‐101 as an Orally Active Agent That Blocks Angiogenesis in Liver Metastases of Human Stomach Cancer Cells

TAC‐101 (4‐[3,5‐bis(trimethylsilyl)benzamido]benzoic acid) is a novel, synthetic retinoid that is effective against liver metastases of human gastrointestinal cancer cells such as the human stomach carcinoma line AZ‐521 in animal models, and is currently in use in phase I cancer trials. However, the...

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Detalles Bibliográficos
Autores principales: Oikawa, Tsutomu, Murakami, Koji, Sano, Masaki, Shibata, Jiro, Wierzba, Konstanty, Yamada, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926657/
https://www.ncbi.nlm.nih.gov/pubmed/11714448
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02144.x