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Introduction of Clusterin Gene into Human Renal Cell Carcinoma Cells Enhances Their Resistance to Cytotoxic Chemotherapy through Inhibition of Apoptosis both in vitro and in vivo

Recent studies have revealed the powerful antiapoptotic activity of clusterin in various malignant tumors; however, the significance of clusterin expression in the acquisition of a resistant phenotype against several kinds of treatment in human renal cell carcinoma (RCC) has not been well characteri...

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Detalles Bibliográficos
Autores principales: Hara, Isao, Miyake, Hideaki, Gleave, Martin E., Kamidono, Sadao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926662/
https://www.ncbi.nlm.nih.gov/pubmed/11714447
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02143.x