High Frequency of Deletions at the Hypoxanthine‐guanine Phosphoribosyl‐transferase Locus in an Ataxia‐telangiectasia Lymphoblastoid Cell Line Irradiated with y‐Rays

The molecular nature of y‐ray‐induced mutations at the hypoxanthine‐guanine phosphoribosyl‐transferase (HPRT) locus in an ataxia‐telangiectasia (A‐T) lymphoblastoid cell line was investigated. Twelve of 15 y‐ray‐induced HPRT‐deficient mutants showed deletions. Eight of them had lost the entire HPRT...

Descripción completa

Detalles Bibliográficos
Autores principales: Tachibana, Akira, Tatsumi, Kouichi, Furuno‐Fukushi, Ikuko, Sasaki, Masao S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926665/
https://www.ncbi.nlm.nih.gov/pubmed/11714443
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02139.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926665/
https://www.ncbi.nlm.nih.gov/pubmed/11714443
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02139.x

Ejemplares similares