Paclitaxel and SN‐38 Overcome Cisplatin Resistance of Ovarian Cancer Cell Lines by Down‐regulating the Influx and Efflux System of Cisplatin

Cisplatin (DDP) is one of the key drugs used to treat patients with ovarian cancer, although resistance to DDP can occur. Paclitaxel and SN‐38 (an active metabolite of irinotecan (CPT‐11)) are two drugs that are effective in patients with DDP‐resistant ovarian cancer. To study how these drugs may ov...

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Detalles Bibliográficos
Autores principales: Komuro, Yuuki, Udagawa, Yasuhiro, Susumu, Nobuyuki, Aoki, Daisuke, Kubota, Tetsuro, Nozawa, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926666/
https://www.ncbi.nlm.nih.gov/pubmed/11714450
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02146.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926666/
https://www.ncbi.nlm.nih.gov/pubmed/11714450
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02146.x

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