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CPT‐11 May Provide Therapeutic Efficacy for Esophageal Squamous Cell Cancer and the Effects Correlate with the Level of DNA Topoisomerase I Protein

CPT‐11 is a potent anti‐cancer drug and a specific inhibitor of DNA topoisomerase I (Topo I). In this study, we aim to evaluate the effects of CPT‐11 on esophageal squamous cell cancers (ESCC) and to determine the correlation between the effects and the levels of Topo I expression. We examined the g...

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Detalles Bibliográficos
Autores principales: Nakajima, Yasuaki, Miyake, Satoshi, Nagai, Kagami, Kawano, Tatsuyuki, Iwai, Takehisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926676/
https://www.ncbi.nlm.nih.gov/pubmed/11749700
http://dx.doi.org/10.1111/j.1349-7006.2001.tb02158.x