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Hexosaminidase‐altered Aberrant Crypts, Carrying Decreased Hexosaminidase α and β Subunit mRNAs, in Colon of 1,2‐Dimethylhydrazine‐treated Rats

Aberrant crypt foci (ACF), consisting of morphologically irregular crypts, are thought to be precancerous lesions for colon cancers. For their molecular analysis, it is necessary to avoid contamination with adjacent normal crypts and stromal cells. Decreased hexosaminidase activity in ACF, which has...

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Detalles Bibliográficos
Autores principales: Tsukamoto, Tetsuya, Fukami, Hiroko, Yamanaka, Shoji, Yamaguchi, Akira, Nakanishi, Hayao, Sakai, Hiroki, Aoki, Ichiro, Tatematsu, Masae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926690/
https://www.ncbi.nlm.nih.gov/pubmed/11223539
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01072.x