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Contribution of Caspase‐3 Differs by p53 Status in Apoptosis Induced by X‐Irradiation

We investigated the effect of p53 status on involvement of caspase‐3 activation in cell death induced by X‐irradiation, using rat embryonic fibroblasts (REFs) transduced with a temperature‐sensitive mutant (mt) p53 gene. Cells with wild‐type (wt) p53 showed greater resistance to X‐irradiation than c...

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Detalles Bibliográficos
Autores principales: Kobayashi, Daisuke, Tokino, Takashi, Watanabe, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926727/
https://www.ncbi.nlm.nih.gov/pubmed/11346471
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01118.x