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Contribution of Caspase‐3 Differs by p53 Status in Apoptosis Induced by X‐Irradiation
We investigated the effect of p53 status on involvement of caspase‐3 activation in cell death induced by X‐irradiation, using rat embryonic fibroblasts (REFs) transduced with a temperature‐sensitive mutant (mt) p53 gene. Cells with wild‐type (wt) p53 showed greater resistance to X‐irradiation than c...
Autores principales: | Kobayashi, Daisuke, Tokino, Takashi, Watanabe, Naoki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2001
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926727/ https://www.ncbi.nlm.nih.gov/pubmed/11346471 http://dx.doi.org/10.1111/j.1349-7006.2001.tb01118.x |
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