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Monitoring of Intracellular l‐βD‐Arabinofuranosylcytosine 5′‐Triphosphate in 1‐β‐D‐Arabinofuranosylcytosine Therapy at Low and Conventional Doses

1‐β‐D‐Arabinofuranosylcytosine (ara‐C) is used empirically at a low, conventional, or high dose. Ara‐C therapy may be optimal if it is directed by the clinical pharmacokinetics of the intracellular active metabolite of ara‐C, 1‐β‐D‐arabinofuranosylcytosine 5′‐triphosphate (ara‐CTP). However, ara‐CTP...

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Detalles Bibliográficos
Autores principales: Yamauchi, Takahiro, Kawai, Yasukazu, Kishi, Shinji, Goto, Nobuyuki, Urasaki, Yoshimasa, Imamura, Shin, Fukushima, Toshihiro, Yoshida, Akira, Iwasaki, Hiromichi, Tsutani, Hiroshi, Masada, Mikio, Ueda, Takanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926735/
https://www.ncbi.nlm.nih.gov/pubmed/11376564
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01128.x