In vivo Effects of a Histone Deacetylase Inhibitor, FK228, on Human Acute Promyelocytic Leukemia in NOD/Shi‐scid/scid Mice

Histone acetylation and deacetylation are closely linked to transcriptional activation and repression, respectively. In acute promyelocytic leukemia (APL), histone deacetylase inhibitors (HDACIs) have a synergistic effect with all‐iraws retinoic acid (ATRA) in vitro to induce differentiation. Here w...

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Detalles Bibliográficos
Autores principales: Kosugi, Hiroshi, Ito, Masafumi, Yamamoto, Yukiya, Towatari, Masayuki, Ito, Mamoru, Ueda, Ryuzo, Saito, Hidehiko, Naoe, Tomoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926744/
https://www.ncbi.nlm.nih.gov/pubmed/11376562
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01126.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926744/
https://www.ncbi.nlm.nih.gov/pubmed/11376562
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01126.x

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