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Frameshift Mutations at Mononucleotide Repeats in RAD50 Recombinational DNA Repair Gene in Colorectal Cancers with Microsatellite Instability

To identify additional genes targeted for microsatellite instability (MSI), we search for human genes which contain mononucleotide repeats in their coding region, selected 7 genes (RAD50, DNA‐PKcs, FLASH, Apaf‐1, XPG, CtIP, and MLSN1), and analyzed frameshift mutations in them. Here we report that 6...

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Detalles Bibliográficos
Autores principales: Ikenoue, Tsuneo, Togo, Goichi, Nagai, Keiichi, Ijichi, Hideaki, Kato, Jun, Yamaji, Yutaka, Okamoto, Makoto, Kato, Naoya, Kawabe, Takao, Tanaka, Atsushi, Matsumura, Masayuki, Shiratori, Yasushi, Omata, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926751/
https://www.ncbi.nlm.nih.gov/pubmed/11429044
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01134.x