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Coordinate Involvement of Cell Cycle Arrest and Apoptosis Strengthen the Effect of FTY720

A novel reagent, FTY720 (2‐amino‐2‐[2‐(4‐octylphenyl)ethyl]‐l,3‐propanediol hydrochloride), has been shown to induce a significant decrease of lymphocytes and lymphoma cells and is expected to be a potent immunosuppressant and anti‐tumor drug. The decrease in lymphocytes and lymphoma cells is mainly...

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Detalles Bibliográficos
Autores principales: Nagahara, Yukitoshi, Matsuoka, Yumiko, Saito, Kaoru, Ikekita, Masahiko, Higuchi, Shigesada, Shinomiya, Takahisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926763/
https://www.ncbi.nlm.nih.gov/pubmed/11429058
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01148.x