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Expression of ICAD‐L and ICAD‐S in Human Brain Tumor and Its Cleavage upon Activation of Apoptosis by Anti‐Fas Antibody

ICAD/DFF is a downstream molecule of caspases, participating in nuclear DNA fragmentation during apoptosis. ICAD/DFF binds CAD/DFF40 and inhibits its DNase activity. ICAD/DFF has two alternative isoforms, long isoform (ICAD‐L/DFF45) and short isoform (ICAD‐S/DFF35). We have studied the presence and...

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Detalles Bibliográficos
Autores principales: Masuoka, Jun, Shiraishi, Tetsuya, Ichinose, Makoto, Mineta, Toshihiro, Tabuchi, Kazuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5926781/
https://www.ncbi.nlm.nih.gov/pubmed/11473733
http://dx.doi.org/10.1111/j.1349-7006.2001.tb01165.x